International Pediatric COVID-19 Severity Over the Course of the Pandemic
This cohort study suggested that while intensive care unit admission decreased over the course of the pandemic in all age groups, ventilatory and oxygen support did not decrease over time in children aged younger than 5 years.
Pandemic preparedness, response and recovery: Lessons learnt for global pharmacy
Investing in science and innovation is one of six key areas of development needed to prepare for future pandemics, according to a new report conducted by the International Pharmaceutical Federation (FIP).
Co-evolution of immunity and seasonal influenza viruses
Seasonal influenza viruses cause recurring global epidemics by continually evolving to escape host immunity. The viral constraints and host immune responses that limit and drive the evolution of these viruses are increasingly well understood.
The SARS-CoV-2 Spike Protein Mutation Explorer: using an interactive application to improve the public understanding of SARS-CoV-2 variants of concern
The rapid evolution of SARS-CoV-2 resulted in variations in the spike that enhanced transmissibility or weakened vaccine protection.
TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by the availability of entry receptors on host cells.
Dispersal patterns and influence of air travel during the global expansion of SARS-CoV-2 variants of concern
Long Covid: clues about causes
This investigated the monocyte and inflammatory profiles of individuals who were hospitalised with COVID-19 during the acute phase and the convalescent period.
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination
This study demonstrates durable yet compartmentalised nasal IgA and plasma antibody responses to SARSCoV-2 after infection and subsequent vaccination.
Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation
T cell responses against infections and cancer are directed by conventional dendritic cells (cDCs) in lymph nodes distant from the site of challenge.
Molecular and phenotypic characteristics of RSV infections in infants during two nirsevimab randomized clinical trials
Nirsevimab is a monoclonal antibody that binds to the RSV fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical trials, infants received one dose of nirsevimab or placebo before their first RSV season.
Policy & Recommendations
Eurostat presents Influenza statistics from 2019, 2020 and 2021
This article presents an overview of European Union (EU) statistics related to influenza.
WHO Europe and EPHA sign new MoU to strengthen collaboration for better health and well-being in Europe
The European Public Health Alliance have signed a memorandum of understanding with WHO Europe to enhance their partnership. Both organisations will work closely to address key health challenges and drive positive change.