Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adults
Frequency, phenotype and T-cell receptor (TCR) composition of influenza-specific CD8+ T-cells directed at the prominent A2/M158 influenza epitope change across the human lifespan.
Neuraminidase-specific antibodies drive differential cross-protection between contemporary FLUBV lineages
The two influenza B virus (FLUBV) lineages have continuously diverged from each other since the 1980s, with recent (post-2015) viruses exhibiting accelerated evolutionary rate.
Age and Latent Cytomegalovirus Infection Do Not Affect the Magnitude of De Novo SARS-CoV-2-Specific CD8+ T Cell Responses
Immunosenescence, age-related immune dysregulation, reduces immunity upon vaccinations and infections.
COVID-19 vaccine during pregnancy reduces risks to mother and baby
Pregnant women with COVID-19 are more likely to develop severe COVID-19 and related ill health than non-pregnant women of similar age.
News
Policy & Recommendations
Joint Action on REspiratory Diseases (JARED) launched
A new joint action focusing on tackling chronic respiratory diseases was recently launched. Backed by the EU4Health programme, the 3-year initiative aims to improve lung health across Europe through innovative digital health technologies.
MEPs establish life-course immunisation group at the European Parliament
Launched in Brussels on 30 January to drive political momentum for broader vaccine uptake across all stages of life. The group is co-chaired by Croatian MEP Tomislav Sokol and Lithuanian MEP Vytenis Andriukaitis, a former European Commissioner for Health.
A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology
Human parainfluenza virus type 3 (HPIV-3) can cause severe respiratory tract infections. There are no convenient small-animal infection models.