Characterization of the glycoproteins of novel fish influenza B-like viruses
Novel influenza-like virus sequences previously identified in fish and amphibians were found to cluster as a sister clade of influenza B viruses, but have thus far remained uncharacterized.
Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adults
Frequency, phenotype and T-cell receptor (TCR) composition of influenza-specific CD8+ T-cells directed at the prominent A2/M158 influenza epitope change across the human lifespan.
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Why not a 95-95-95 strategy for influenza by 2030?
This strategy aims for 95% of individuals infected with HIV to know their status, 95% of those infected to be under effective treatment, and 95% of those receiving treatment to achieve viral suppression.
A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses
Anti-influenza therapeutics remain essential for the control of influenza infections, which may require hospitalization for the most severe cases.
Neuraminidase-specific antibodies drive differential cross-protection between contemporary FLUBV lineages
The two influenza B virus (FLUBV) lineages have continuously diverged from each other since the 1980s, with recent (post-2015) viruses exhibiting accelerated evolutionary rate.
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Policy & Recommendations
Europe needs a sustainably funded influenza research and response network
Six ESWI Board Members, led by Prof. Florian Krammer, together with a long list of prominent European scientists specialised in virology, immunology and epidemiology, have recently published a commentary in The Lancet Infectious Diseases.
Next-generation seasonal influenza virus vaccines need a neuraminidase component
This commentary highlights the potential need to incorporate neuraminidase components into future influenza vaccines
Interim data on flu vaccines estimate overall moderate protection in Europe and China
Estimates of current mid-season flu vaccine effectiveness (VE) in Europe and China range from 32% to 58% overall, with greater protection against influenza B than A, according to three studies published in Eurosurveillance.