Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adults
Frequency, phenotype and T-cell receptor (TCR) composition of influenza-specific CD8+ T-cells directed at the prominent A2/M158 influenza epitope change across the human lifespan.
News
Policy & Recommendations
Promoting vaccination amongst the elderly with VITAL’s new tools
The VITAL project published an educational platform as well as a toolbox to boost vaccination uptake amongst older people.
Podcast Series: hMPV – A Common Yet Unknown Respiratory Threat
In this 3-part podcast series, the International Federation on Ageing (IFA) aims to raise awareness of hMPV. The series will feature scientists, clinicians and the voices of older people and groups representing those most at risk of serious disease.
Influenza and Aging: Clinical Manifestations, Complications, and Treatment Approaches in Older Adults
Older adults, especially those over 65 years of age, face increased risks of immune senescence, chronic comorbidities, and decreased vaccine efficacy.
The respiratory syncytial virus vaccine and monoclonal antibody landscape: the road to global access
This Review provides an overview of RSV vaccines highlighting different target populations, antigens, and trial results. As RSV vaccines have not yet reached low-income and middle-income countries, next steps are outlined to minimise the delay.
What are the risks of RSV infections for older individuals?
ESWI addresses common questions and misconceptions amongst the general public regarding influenza, COVID-19 and RSV. These responses, elaborated by ESWI Board Members and coalition partners, aim to increase public awareness and prevent misinformation.
Article
Scientific Papers
Age, comorbidity burden and late presentation are significant predictors of hospitalization length and acute respiratory failure in patients with influenza
Influenza viruses are responsible for a high number of infections and hospitalizations every year.
Respiratory Syncytial Virus Infection in Older Adults: An Update
Respiratory syncytial virus (RSV) infection represents one of the most common infections during childhood, with significant morbidity and mortality in newborns and in the early years of life.