SnotWatch: Mapping respiratory microbiology information to inform health outcomes
It collates data on health outcomes alongside laboratory results for virus tests. This creates a large and rich data platform, which will be used to accurately describe and predict health problems related to common viruses in the community.
Influenza vaccine effectiveness from nine studies during drifted A(H3N2) subclade K predominance, Europe, September 2025 to January 2026
The European 2025/26 influenza season is dominated by the influenza A(H3N2) virus, with most sequenced viruses belonging to subclade K, genetically drifted from the vaccine virus, raising concerns around vaccine effectiveness.
Interim 2025/26 influenza vaccine effectiveness estimates with immuno-epidemiological considerations for A(H3N2) subclade K protection, Canada, January 2026
In a pre-season influenza risk assessment publicly posted in October 2025, Canadian investigators used global genomic and antigenic surveillance data to highlight important mutations in circulating influenza A(H3N2) viruses.
Antigenic Drift and Antivaccine Shift in the 2025–2026 Influenza Season
Both viral and host factors have contributed to the intensity of influenza activity during the 2025–2026 season. Some of these factors can be managed, whereas others are largely beyond human control.
Risk of Cardiorespiratory Events Following Respiratory Syncytial Virus–Related Hospitalization
In this self-controlled case series study of 11 887 patients, the risk of cardiorespiratory events after RSV-related hospitalization was significantly higher than during the control period.
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase
Human influenza A viruses escape antibody-mediated immunity through changes in the hemagglutinin (HA) and neuraminidase (NA) glycoproteins.
Estimated impact of 2022–2023 influenza vaccines on annual hospital burden in the United States
Annual influenza epidemics in the United States cause hundreds of thousands of hospitalizations.
Global Respiratory Virus Activity by WHO
Global influenza and COVID-19 activity stayed low in late October 2025. COVID-19 was more common in northern regions, while influenza spread mainly in tropical areas.