Cross-reactive H5N1 Neuraminidase Antibodies by Age and Influenza A Imprinting Cohorts of the Past Century: Population-Based Serosurvey, British Columbia, Canada
Oxford Academic, The Journal of Infectious Diseases
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January 16 2026
Preexisting immunity to emerging influenza viruses informs pandemic risk assessment. We compared cross-reactive neuraminidase antibody levels against avian influenza A(H5N1) by age and birth (imprinting) cohorts defined by periods of human influenza A subtype (H1N1, H2N2, or H3N2) circulation over the past century.
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