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Eight vaccines linked to a lower risk of dementia

GAVI, The Vaccine Alliance
|
July 15 2026

This article summarises key studies related to eight routine adult vaccines (Shingles, RSV, Influenza, DTP, Pneumococcal, Hepatitis A, Hepatitis B, and Typhoid) which have each been linked to a reduced risk of dementia.

Key messages: 

  • "Multiple large observational studies have found that routine adult vaccines are associated with a reduced risk of dementia, with some showing risk reductions of 25% to 40%.
  • The strongest evidence exists for shingles, flu, RSV, pneumococcal and diphtheria, tetanus and pertussis-containing (DTP) vaccines.
  • Researchers believe vaccination may reduce dementia risk by preventing infections that cause brain inflammation, though some evidence points to a more general immune effect."
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